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HBOT
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A pilot study
Kevin Barrett,
M.D., F.A.C.P. - Professor of Hyperbaric Medicine, University of
Texas Medical Branch, Galveston, TX, USA
Abstract
Authors:
Kevin
F. Barrett MD, Kevan P. Corson CHt, Jon T. Mader MD
Title:
Pediatric cerebral palsy treated by 1. 5 ATA hyperbaric oxygen
- a pilot study.
Objective:
To determine if 1. 5 ATA hyperbaric oxygen therapy can
ameliorate the neurologic deficits associated with pediatric
cerebral palsy.
Background: Numerous
anecdotal reports attest to the amelioration of neurologic
deficits in a variety of chronic cerebral insults including
cerebral palsy. Improvement is Attributed to the metabolic up
regulation through improved local cerebral blood flow in a residual chronic Ischemic penumbra.
Methods: Five
children, average age 41.8 months, were treated with 1.5 ATA
liyperbaric oxygen therapy (HBOT) for a total of sixty
treatments administered for one hour daily, five days a week. A
modified test of gross motor and fine motor function I GMFM-M)
and a modified Ashworth Spasticity Scale were employed before
and after liyperbaric therapy.
One patient with cortical blindness was assessed with visual
evoked potentials before and -ifter HBOT. One patient dropped
out of the study before completion. Information was obtained on
only four patients.
Results:
Modest decreases in spasticity and improvements in the modified
GMFM ,;cores for all patients completing the study. Cortical
visual evoked potentials, which ,were absent before therapy in
one patient were measurable after HBOT.
Conclusion: Hyperbaric oxygen
therapy effected improvements in tests of gross motor ,and fine
motor function and decreased spasticity as measured by a
modified Ashworth spasticity score's patients with chronic
cerebral palsy. Functional reorganization in the visual cortex
is suggested by the reappearance of visual evoked
potentials.
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