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Therapies
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Brain SPECT
Santa Monica- UCLA Medical Center
In the last few years Hyperbaric Oxygen
Therapy
(HBOTX) has been to have a new
therapeutic endpoint- the improvement of long term brain
disorders. Brain SPECT imaging has begun to be utilized in
evaluating the efforts of the therapy.
Imaging of the brain is divided into two
classes: anatomic and functional. The two types of anatomic
imaging are CT and NM- "Cat" scanning and magnetic resonance
imaging. The question these address is: dose the brain's
physical structure Icok normal or abnormal. But of greater
importance is: however the structure app (Iars, is it
functioniniz? If so, is the observed function normal or
difference than normal.
Functional imaging is known as SPECT and
PET - single photon emission computered Tomography and positron
emission Tomography. These show brain function because the
distribution of an injected radioactive tracer is directly
related to functions such as brain blood flow and/or cellular
activity. Both of these technologies have been well developed
and used routinely over the last fifteen years. ( Another form
of functional imaging that is being studied for possible future
use is fNM- "functional" NM. There are presently no experience
of using fNM with HBOTX.)
Brain SPECT imaging is the only
routinely used imaging evaluation of HBOTX. This is because it
is the only one that is widely available outside of medical
university settings, and because shows blood flow and function
in both normal and abnormal functional states. Its basic
decision factor is to differentiate normal from abnormal tracer
distribution on the scan pictures. This work adequately with
localized abnormality such as a stroke, but much less well with
what we understand to be more diffuse and variable abnormalities
such as near drowning episodes, toxic substance exposure and
long term neurologic conditions such as drown episodes, toxic
substance exposure and long-term neurologic conditions such as
cerebral palsy and autism.
Thus the need exists for a quantitive
method in which computer-aided analysis can categorize the
variablility of abnormality and develop standards and databases
for normality and specific adnormalities, to express brain
functional finding in quatitative color-coded images that are
easier for others. To understand, and compare brain SPECT
changes with HBOT.
A special thank you to the countless Drs and children whom have
made this research possible. All information contained within
these pages are the sole property of the Dr.s and experts that
have spent the countless hours researching for OUR CHILDREN.
Please read each page of content and please contact your local
congressmen and appropriate government officials today. Thank
you.
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The Cerebral Palsy Network©1997/2014. All graphics are the exclusive property of CPN, unless otherwise indicated. Contact Cerebral Palsy Network for further information. Last updated 05/04/14 |